Patrick Collison is a thoughtful communicator who shares insights on technology, progress, and building companies. Here are some of the most illuminating conversations and presentations featuring his ideas.

Featured Podcasts & Interviews

Dwarkesh Patel Podcast

February 2024

A wide-ranging conversation covering Stripe's mission to process $1 trillion annually, building multi-decade APIs and companies, Arc Institute's work on biomedical research, advice for people in their twenties, and thoughts on Progress Studies[11].

Stripe Strategy Arc Institute Career Advice Progress Studies
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Running Your Company - Y Combinator

Various

Patrick discusses how to effectively run a startup with Y Combinator partner Adora Cheung. The conversation covers operational best practices, scaling challenges, and the lessons learned from building Stripe[22].

Startup Operations Y Combinator Scaling
Watch on YC Library →

Startup Grind Interview

2012

An early interview with Patrick, just 6 months into Stripe's journey. He discusses tackling one of the hardest problems on the internet, the experience of going through Y Combinator, and building Stripe's first prototype in Buenos Aires[21].

Early Stripe Entrepreneurship Payment Systems
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Interview with Noah Smith

March 2021

A comprehensive email interview covering the future of technology, what kinds of innovation humanity needs, whether innovation has slowed down, the roles of government and private sector, research funding reform, and international competition[14].

Innovation Progress Studies Scientific Research
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Cursor CEO Interview

July 2024

Patrick discusses his use of AI tools, including how he relies on tools like Grok to answer questions while reading, and his thoughts on AI for writing and coding[15].

AI Tools Cursor Developer Tools

Elad Gil - High Growth Handbook

Various

An in-depth conversation about culture, scaling, dealing with naysayers, and opening new offices. Patrick discusses how culture must evolve as companies grow and the importance of being explicit about that evolution[16].

Company Culture Scaling Management
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Stripe Sessions

AMA with Patrick and John Collison (2024)

April 2024

The Collison brothers answer questions about Stripe's future, craft and beauty in product development, lessons from Auctomatic, and their philosophy on building multi-decade companies. Moderated by Fidji Simo, CEO of Instacart[20].

Stripe Sessions Craft & Beauty Long-term Thinking
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AMA with Patrick and John Collison (2025)

May 2025

A more recent AMA discussing Stripe's AI initiatives including their use of Cursor for coding, AI minions for bug fixing, balancing investment in existing products versus new opportunities, and thoughts on housing supply[17].

AI Integration Product Development Developer Tools
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Other Notable Appearances

Retool Summit Interview

Patrick discusses AI agents, flexible tools, Stripe's internal "minions" for automated development, and his pragmatic philosophy for building software[18].

Read summary →

The Social Radars Podcast

Patrick and John discuss their journey building Stripe, lessons from Y Combinator, and their approach to company building[19].

Listen →

Reid Hoffman & John Lilly Interviews

Multiple interviews discussing Stripe's growth, Patrick's reading habits, and thoughts on technological progress[12].

Ezra Klein Podcast

A thoughtful conversation about technology, progress, and the future of work and innovation.

Shane Parrish (The Knowledge Project)

Deep dive into mental models, decision-making, and building long-term businesses.

Tim Ferriss Show

Discussion of Patrick's reading habits, learning strategies, and approach to entrepreneurship.

Where to Find More

Patrick maintains a website at patrickcollison.com where he shares his reading lists, thoughts on various topics, and links to interviews. He's also active on Twitter/X @patrickc where he shares insights and engages with ideas around progress, science, and technology.